{"id":9693,"date":"2024-08-15T14:13:03","date_gmt":"2024-08-15T12:13:03","guid":{"rendered":"https:\/\/apolinar.eu\/?page_id=9693"},"modified":"2024-08-15T14:13:03","modified_gmt":"2024-08-15T12:13:03","slug":"metody-lecby-neplodnosti","status":"publish","type":"page","link":"https:\/\/apolinar.capta.cz\/uk\/centrum-asistovane-reprodukce\/poskytovana-pece\/metody-lecby-neplodnosti\/","title":{"rendered":"Metody l\u00e9\u010dby neplodnosti"},"content":{"rendered":" \r\n \r\n
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Metody l\u00e9\u010dby neplodnosti<\/h2>
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Intrauterinn\u00ed inseminace<\/h3>\r\n
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Je nejm\u00e9n\u011b n\u00e1ro\u010dn\u00e1 metoda asistovan\u00e9 reprodukce, kdy se promyt\u00e9 a zkoncentrovan\u00e9 spermie aplikuj\u00ed tenk\u00fdm plastov\u00fdm katetrem \u017een\u011b p\u0159\u00edmo do d\u011blohy v dob\u011b ovulace. V\u00fdhodou je snadn\u00e9 a neinvazivn\u00ed proveden\u00ed bez nutnosti anestezie. Je vhodn\u00e1 p\u0159edev\u0161\u00edm pro p\u00e1ry, kde mu\u017e m\u00e1 dobr\u00fd nebo hrani\u010dn\u00ed po\u010det pohybliv\u00fdch spermi\u00ed, nebo \u017eena m\u00e1 sn\u00ed\u017eenou prostupnost hlenu d\u011blo\u017en\u00edho hrdla (negativn\u00ed postkoit\u00e1ln\u00ed test).<\/p>\n

\u00dasp\u011b\u0161nost t\u00e9to metody se pohybuje kolem 10 %.<\/p>\n

Inseminac\u00ed lze v p\u0159\u00edpad\u011b pot\u0159eby aplikovat tak\u00e9 d\u00e1rcovsk\u00e9 spermie.<\/p>\n <\/div>\r\n <\/div>\r\n <\/div>\r\n \r\n

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Misky na separaci spermi\u00ed LensHooke CA0 (mikrofluidn\u00ed separa\u010dn\u00ed \u010dipy)<\/h3>\r\n
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Pou\u017eit\u00ed t\u00e9to metody umo\u017e\u0148uje selekci kvalitn\u00edch spermi\u00ed pro proveden\u00ed um\u011bl\u00e9ho oplozen\u00ed na z\u00e1klad\u011b jejich pohybu skrz tenkou membr\u00e1nu s kan\u00e1lky, \u010d\u00edm\u017e je napodobov\u00e1n pohyb spermi\u00ed p\u0159irozen\u00fdm prost\u0159ed\u00edm reproduk\u010dn\u00edho \u00fastroj\u00ed \u017eeny. V\u00fdhodou mikrofluidn\u00edch separa\u010dn\u00edch \u010dip\u016f je, \u017ee pro zpracov\u00e1n\u00ed spermatu nen\u00ed t\u0159eba pou\u017e\u00edvat centrifugaci, co\u017e minimalizuje mechanick\u00e9 po\u0161kozen\u00ed spermi\u00ed a jejich DNA. Do sb\u011brn\u00e9ho d\u016flku \u010dipu skrz kan\u00e1lky procestuj\u00ed pohybliv\u00e9 \u017eivotaschopn\u00e9 spermie, kter\u00e9 se d\u00e1le vyu\u017e\u00edvaj\u00ed pro um\u011bl\u00e9 oplozen\u00ed.<\/p>\n

Jednor\u00e1zov\u00e9 separa\u010dn\u00ed \u010dipy doporu\u010dujeme zejm\u00e9na p\u0159i \u0161patn\u00e9m oplozen\u00ed oocyt\u016f nebo p\u0159i \u0161patn\u00e9m v\u00fdvoji embry\u00ed v p\u0159edchoz\u00edch IVF cyklech a po opakovan\u00fdch potratech. Metodu nelze pou\u017e\u00edt p\u0159i nedosta\u010duj\u00edc\u00edm mno\u017estv\u00ed ejakul\u00e1tu \u010di sn\u00ed\u017een\u00e9m mno\u017estv\u00ed progresivn\u011b pohybliv\u00fdch spermi\u00ed v ejakul\u00e1tu.<\/p>\n <\/div>\r\n <\/div>\r\n <\/div>\r\n \r\n

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ICSI (intracytoplasmatick\u00e1 injekce spermie do oocytu)<\/h3>\r\n
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Jedn\u00e1 se o mikromanipula\u010dn\u00ed techniku oplozen\u00ed, jej\u00edm\u017e principem je vpraven\u00ed spermie do zral\u00e9ho vaj\u00ed\u010dka pomoc\u00ed mikropipety (tenk\u00e9 sklen\u011bn\u00e9 jehly).\"\" Jedn\u00e1 se o velmi precizn\u00ed a efektivn\u00ed metodu, kter\u00e1 se pou\u017e\u00edv\u00e1 v indikovan\u00fdch p\u0159\u00edpadech, a je nezbytn\u00e1 p\u0159i patologick\u00e9m spermiogramu.<\/p>\n <\/div>\r\n <\/div>\r\n <\/div>\r\n \r\n

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IVF (konven\u010dn\u00ed metoda oplozen\u00ed)<\/h3>\r\n
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Jedn\u00e1 se o metodu, b\u011bhem kter\u00e9 doch\u00e1z\u00ed ke spont\u00e1nn\u00edmu oplozen\u00ed vaj\u00ed\u010dka po p\u0159id\u00e1n\u00ed dan\u00e9ho mno\u017estv\u00ed pro\u010di\u0161t\u011bn\u00fdch spermi\u00ed do m\u00e9dia s vaj\u00ed\u010dkem. Spermie pak sv\u00fdm aktivn\u00edm pohybem bi\u010d\u00edkem doputuje k\u202fvaj\u00ed\u010dku, pronikne do n\u011bj a oplodn\u00ed ho. S v\u00fdhodou lze pou\u017e\u00edt p\u0159i kvalitn\u00edm spermiogramu.<\/p>\n <\/div>\r\n <\/div>\r\n <\/div>\r\n \r\n

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Asistovan\u00fd hatching<\/h3>\r\n
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Pomoc\u00ed laseru je provedeno otev\u0159en\u00ed obalu embrya – zony pellucidy. T\u00edmto naru\u0161en\u00edm dojde k usnadn\u011bn\u00ed vycestov\u00e1n\u00ed embrya pro jeho uhn\u00edzd\u011bn\u00ed v d\u011blo\u017en\u00ed sliznici. Jedn\u00e1 se o \u0161etrn\u00fd z\u00e1krok, b\u011bhem kter\u00e9ho nedoch\u00e1z\u00ed k\u202fpo\u0161kozen\u00ed vnit\u0159n\u00edch struktur embrya. Ve standardn\u00edch p\u0159\u00edpadech embryo samo opust\u00ed sv\u016fj obal, pouze v indikovan\u00fdch p\u0159\u00edpadech je asistovan\u00fd hatching vhodn\u00fd.<\/p>\n <\/div>\r\n <\/div>\r\n <\/div>\r\n \r\n

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Embryo Glue<\/h3>\r\n
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Je speci\u00e1ln\u00ed m\u00e9dium pro embryotransfer. Jeho nejpodstatn\u011bj\u0161\u00ed slo\u017ekou je hyaluronan, kter\u00fd je p\u0159irozenou sou\u010d\u00e1st\u00ed prost\u0159ed\u00ed v d\u011bloze. V literatu\u0159e se uv\u00e1d\u00ed, \u017ee \u017een\u00e1m nad 35 let \u010dasto hyaluronan v d\u011blo\u017en\u00edm prost\u0159ed\u00ed chyb\u00ed. Proto jeho p\u0159id\u00e1n\u00ed prost\u0159ednictv\u00edm speci\u00e1ln\u00edho m\u00e9dia Embryo Glue umo\u017en\u00ed snadn\u011bj\u0161\u00ed uhn\u00edzd\u011bn\u00ed embrya v d\u011blo\u017en\u00ed sliznici.<\/p>\n <\/div>\r\n <\/div>\r\n <\/div>\r\n <\/div>\r\n <\/div>\r\n <\/section>\r\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":6,"featured_media":0,"parent":9706,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-9693","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"\nMetody l\u00e9\u010dby neplodnosti - Porodnice U Apolin\u00e1\u0159e<\/title>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"uk_UA\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Metody l\u00e9\u010dby neplodnosti - Porodnice U Apolin\u00e1\u0159e\" \/>\n<meta property=\"og:url\" content=\"https:\/\/apolinar.capta.cz\/uk\/centrum-asistovane-reprodukce\/poskytovana-pece\/metody-lecby-neplodnosti\/\" \/>\n<meta property=\"og:site_name\" content=\"Porodnice U Apolin\u00e1\u0159e\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/apolinar.capta.cz\/uk\/centrum-asistovane-reprodukce\/poskytovana-pece\/metody-lecby-neplodnosti\/\",\"url\":\"https:\/\/apolinar.capta.cz\/uk\/centrum-asistovane-reprodukce\/poskytovana-pece\/metody-lecby-neplodnosti\/\",\"name\":\"Metody l\u00e9\u010dby neplodnosti - Porodnice U Apolin\u00e1\u0159e\",\"isPartOf\":{\"@id\":\"https:\/\/apolinar.capta.cz\/uk\/#website\"},\"datePublished\":\"2024-08-15T12:13:03+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/apolinar.capta.cz\/uk\/centrum-asistovane-reprodukce\/poskytovana-pece\/metody-lecby-neplodnosti\/#breadcrumb\"},\"inLanguage\":\"uk\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/apolinar.capta.cz\/uk\/centrum-asistovane-reprodukce\/poskytovana-pece\/metody-lecby-neplodnosti\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/apolinar.capta.cz\/uk\/centrum-asistovane-reprodukce\/poskytovana-pece\/metody-lecby-neplodnosti\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Dom\u016f\",\"item\":\"https:\/\/apolinar.capta.cz\/uk\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Metody l\u00e9\u010dby neplodnosti\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/apolinar.capta.cz\/uk\/#website\",\"url\":\"https:\/\/apolinar.capta.cz\/uk\/\",\"name\":\"Porodnice U Apolin\u00e1\u0159e\",\"description\":\"Klinika gynekologie, porodnictv\u00ed a neonatologie 1. 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